Townsville Hospital, South Brisbane, Australia;ICON Cancer Care, South Brisbane, Australia.
Mater Pathology, South Brisbane, Australia;Tplays a key oncogenic role in blood cancers, particularly myeloproliferative neoplasms (MPNs) and acute lymphoblastic leukemia (ALL). In normal cells, cytokine-induced activation of the JAK/STAT pathway nal activation, resulting in tightly regulated blood cell production according to need.1 A recurrent mutation in JAK2, leading to the V617F missense mutation in the pseudo-kinase domain, is the most common molecular abnormality in MPNs.52 It results in non-physiological ligand-independent signalling and excess blood cell production. The discovery of this key driver mutation has fast tracked the development of targeted agents that inhibit JAK2, resulting in therapeutic benefit.76 Whilst more than 95% of cases of polycythemia vera (PV) harbour the JAK2V617F mutation, only about 50–60% of cases do so. The rest carry mutations in CALR, MPL, and many other genes at much lower frequencies. For most triple-negative MPNs (i.e., wild type for JAK2, CALR and MPL), a molecular diagnosis is not available because access to clinical next generation sequencing (NGS) platforms is limited or expensive. In addition, there are clinical cases which are difficult to fit into the WHO criteria for MPNs; MPN/MDS, MPN-unclassifiable (MPN-u), and atypical CML (aCML) are good examples of such difficulties.
We report the case of a 78-year-old woman who was referred for hematology consultation after a routine full blood examination (FBE) demonstrated significant abnormalities. She was clinically well at presentation, reporting no notable symptoms. In particular, she reported no bruising, bleeding, infections, fevers, weight loss, night sweats or lethargy. There was no significant past medical history, and the only regular medication was frusemide which she took for fluid retention. On examination, there was no splenomegaly, hepatomegaly or lymphadenopathy. FBE demonstrated a significantly elevated white cell count (WCC) of 21.6×10/L with left shift, including numerous circulating metamyelocytes and myelocytes, and occasional promyelocytes and blast cells. There was also basophilia (0.66×10/L), mild monocytosis (2.8×10/L), and mild thrombocytopenia (72×10/L) (Figure 1A). No dysplasia was noted. Lactate dehydrogenase (LDH) was elevated at 665U/L (reference range 120–250U/L) at time of presentation. In light of the FBE findings, the BCR-ABL1 translocation was searched for via RT-PCR and by FISH for the t(9;22) fusion; both tests were negative. A CT scan of the chest and abdomen was unremarkable, and molecular tests on DNA harvested from whole blood were negative for JAK2 V617F, CALR and MPL gene mutations.
Figure 1.Blood film and bone marrow biopsy findings at diagnosis. A. Peripheral blood film demonstrating basophilia and thrombocytopenia. B. Hypercellular bone marrow fragment. C. Granulocytic hyperplasia and left shift evident on bone marrow aspirate. D. Trephine demonstrating megakaryocytic hyperplasia with several morphologically abnormal/small cells.
A bone marrow examination demonstrated marked abnormalities. The marrow was markedly hypercellular (Figure 1B); granulopoiesis was moderately hyperplastic with a mild left shift; megakaryocytic hyperplasia was also present with occasional small forms and grade 1 fibrosis (i.e., reticulin staining) (Figure 1C–D). Blast cells were present in normal numbers. No As in the blood, FISH for the t(9;22) translocation was negative. Cytogenetics demonstrated a normal female karyotype, and FISH for FIP1LI-PDGFRA and PDGFRB was negative. RT-PCR analysis for rare BCR-ABL breakpoints [including e13a2(b2a2), e14a2(b3a2), e13a3 (b2a3), e14a3(b3a3) and e1a2/p190)] was also negative. A provisional diagnosis of MPN-u was made.
The patient was observed without specific treatment. Over the next three months she reported mild bruising and fatigue. However, there was progression of FBE abnormalities; the WCC steadily increased to 54×10/L, and platelet count decreased to 54×10/L. The hemoglobin remained in the normal range during this time. LDH increased steadily, peaking at 1169U/L four months after presentation but spontaneously returned to ~600U/L without intervention. After a further eight months of stability there was a sudden change in the FBE; platelets decreased to 13×10/L (necessitating platelet transfusion), WCC increased to 82.5×10/L with leucoerythroblastic features, and there was an increasing myeloid left shift. The monocytosis gradually increased to 20×10/L but no dysplastic features were present. Spleen size remained normal at 13cm by abdominal ultrasound. The change in hematologic parameter; the patient remained well, reporting only mild fatigue.
The initial bone marrow DNA specimen was referred for further molecular analysis using a custom designed AmpliSeq panel run on an Ion Torrent PGM machine.11 Using this assay, just three single nucleotide variants were detected in >200kb of sequenced DNA: (i) a heterozygous SNV, c.1972G>A, in JAK1 leading to a predicted missense mutation, V658I (Figure 2A); (ii) a heterozygous insertion, c.27_28insT, leading to a predicted frameshift in DNMT3A, which has not ; it was considered most likely to be a sequencing error, and (iii) a SNV, c.1124G>T, in ETV6 which is predicted to lead to a conservative amino acid change, G375V. This has not been reported in COSMIC and is not in a functionally critical region of the protein, so was considered unlikely to be pathogenic. The DNA sequences of all the exons of JAK2, MPL, CALR, CBL, SETBP1, SRSF1 and all the other genes on the panel, including those previously linked with aCML and CMML,13 were normal.
Activating mutations of JAK1 have mostly been reported in T-cell prolymphocytic leukemia14 and acute lymphoblastic leukemia15 where it has been shown to confer a poorer prognosis as well as non-hematologic malignancies.16 Transduction of V658F, V658L and V658I variants of JAK1 lead to factor- independent cell growth of BaF3 cells, whereas transduction of wild type JAK1 does not,17 so the mutation is unquestionably pathogenic. The valine residue at amino acid 658 in JAK1 is functionally equivalent to V617 in JAK2 (Figure 2B); i.e., it is critically important for negative regulation of JAK kinase activity. To our knowledge, JAK1 mutations have never been described in MPNs or CMML, so this is the first case report. JAK1 is highly expressed in lymphoid and myeloid cell lineages, particularly granulocytes, but it is poorly expressed in megakaryocyte-erythroid progenitors (MEPs) and their erythroid and megakaryocytic progeny compared with JAK2 (Figure 2C).18 It is therefore not surprising that gain-of-function mutations lead to a proliferation of myeloid cells rather than erythroid cells (i.e., PV) or platelets (i.e., ET).
Suzanne O. Arulogun, Hock-Lai Choong, Debbie Taylor, Paula Ambrosoli, Graham Magor, Ian M. Irving, Tee-Beng Keng, Andrew C. Perkins. JAK1 somatic mutation in a m8):e324-e327; https://doi.org/10.3324/haematol.2017.170266.


Abstract Scope FeMnCoCr based high entropy alloys (HEA) are one of the prominent, metastable, multi-component systems that exhibit the unique behavior of transformation induced plasticity (TRIP). The emergence of HCP phase leading to martensitic microstructure during deformation from the metastable parent FCC solid solution phase provides the much-required phase-interface strengthening without compromising the ductility. However, to further improve the mechanical properties of these metastable alloys especially the yield strength, the TRIP effect alone appears to be not sufficient. Hence, this presentation will focus on the experimental design aspects including combinatorial synthesis of compositionally tailored alloys that can exhibit unique microstructures with concomitant precipitation strengthening in FeMnCoCr based HEA system. The crucial challenge of inducing nanoscale precipitate phases that are chemically homogenous in the metastable, FCC structured, low-stacking fault energy solid solution matrix without disturbing its unique behavior of TRIP will be discussed.


Dr. Mugheer Al Khaili, ADEC director general, said: "Competitions such as Imagine Us are great ways to challenge our students, while allowing them to explore their abilities and passion. Competitions are great ways; ge."


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You are here: Home > Majority of England lives...
Majority of England lives within 20 minutes of a GP, report shows
The majority (84.8%) of the population in England is estimated to live within 20 minutes walk of a GP premises
7 May, 2015 11:06 AM. This is lower (81.2%) in the most affluent areas, and higher (98.2%), new research has found.
Commenting on the report Access all Areas? An area-level analysis of accessibility to General Practice and Community Pharmacy services in England by urbanity and social deprivationalso encouraging to see that patients living in areas of deprivation have easier than average access to their GP – and even easier access to a community pharmacy, where they can receive advice about medicines, and how to manage minor ailments.
“However, access to a local surgery is one thing – being able to see a GP is another… GPs and our teams are currently making 370m patient consultations a year – 70m more than we were five years ago – yet the general practice workforce has remained relatively stagnant. The current workforce is also ageing, and as more GPs approach retirement age, our own research has shown that more than 500 practices are under threat of closure,” she said.
The report suggests ategration of community pharmacies and GP practices, which may give patients better access, as at present, the current waiting time for a non-urgent GP appointment is approximately 9 days. Previous research also suggests that for some services, due to the ease of access, community pharmacies are patients preferred location if possible, the report said.
“xplore different ways of working, such as pharmacists working as part of the practice team, and new models of care, such as practices working together in federations to pool resources in order to deliver more and better services to patients, wherever they live,” Baker said.
The report was created by Adam Todd, Alison Copeland, Andy Husband, Adetayo Kasimand Clare Bambra.


Editor’s Note: Swift 3.0 for Raspberry Pi 2 and Pi 3 is now available!
Again, a warning!
I have a pi 3 and it works as well. Just follow the instructions above. I’m only wondering if Swift 3.0 is also available for the pi?
Hi, thanks for your great effort in the Swift open source world. I have a Raspberry Pi 3 with Swift 2.2 installed via one of your tutorials, working great except that the swift-build binary is not included. Is there a way to solve this?
This might be a long shot, but what could be a viable route to getting a GUI up on the Raspberry Pi Touch Display using Swift?
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week. Sitting in the WTF, watching it pass, and then choosing to focus on the positive parts of the experience is the physical part (and the mental workout) of your beginning to create new neural pathways. But that initial awkwardness is mostly felt by them, and it soon dissipates if I don't make it an issue. Sometimes, she would have one, other times, we’d both be sober.Feel better, look better, lose weight, save money and have better relationships. The irrepressible feelings of joy behind this kidlike behavior, which would also sometimes spill out as fits of uncontrollable laughter, usually kicked in only after at least three weeks of being booze-free—as if that’s how long it took for the dregs of my last “drunk” to completely leave my system.
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New Belvoir Cricket Pavilion and school to go ahead
‘most important of all is to realise that while physical access must be limited to the particular uses for which every piece of land is designated, visual access is also part of recreation and to that every use can be made to contribute’
Plans to go ahead


After a testing week following the big disappointment of defeat at Bournville, Hinckley responded with a much improved intensity and while things were nowhere near perfect, there were some excellent improvements which are a great base to work off.
The game then began to settle down, however Hinckley continued to dominate and after 20 minutes Constant had his second score, driving through a defender to dot down from close range, with Smith again converting.
On the stroke of half-time, Robertson scored a converted try for the visitors to ensure that they were still in the game at the break. However Hinckley made sure that these hopes were all but taken away within moments of the restart.
The impressive Phil Brocken on his debut forced a turnover on the visiting 22 and the ball was moved wide to Constant who had a comfortable run in underneath the posts to secure the bonus point. Smith added his fourth conversion.
The counter attack continued to be a weapon with Hinckley scoring again in broken field. This time it came from a Kris McFedries tap penalty on his own 22. He made it into the opposition half before floating the ball to Constant who finished well in the left hand corner.
By this point it was close to one-way traffic although Derby did make a slightly bizarre decision to kick a penalty to bring the score back to 36-13. However soon after Hinckley’s sixth try came. Brocken made a break on the half way and was dragged down just a couple of metres from the line. With Derby struggling to get back from the resulting ruck, Tommy Walsh fed Smith to give him one of the easiest tries which anyone will ever score, which he again converted.
Hinckley: Culpin, Howe, Buckley, Harris, Constant; Smith, McFedries; Cunningham (c), Ball, Peck, Salt, Marshall, Fearn, Avent, Saxon. Reps: Walsh, Barratt, Brocken. </s>  41 56 Comments Loading... Reply ClediadeW 8:30 AM on February 16, 2022 Anvohz  hydroxychloroquine buy online cialis efectos colaterales Ahhjnl Reply ClediadeW 2:09 AM on February 1, 2022 Xogolr plaquenil lupus Reply Unrepay 4:30 PM on January 28, 2022 Prednisone Mfnmew Reply toittejem 10:43 PM on January 24, 2022 costco prescription cialis sottnolliz difference between levitra viagra and cialis Icogsvop Reply buy cialis online no prescription 1:39 PM on December 6, 2021 Discount Pfizer Viagra Reply cequips 10:38 AM on December 5, 2021 hydroxychloroquine order Reply Drarhoors 9:42 AM on December 5, 2021 gabapentin generic name Reply joyhomy 5:18 PM on December 3, 2021 where to buy plaquenil Reply peebtency 3:42 PM on November 20, 2021 Can Keflex Help A Toothache cheap generic cialis Reply Hawdrarne 1:19 PM on November 20, 2021 Buy Generic Propecia Online where to buy viagra without a prescription Reply Atolbox 7:21 PM on November 14, 2021 Prednisone Reply Prednisone 2:37 PM on November 13, 2021 Buy Celebrex From Canada Reply ivermectin pour on 3:25 AM on November 13, 2021 Comprar Cialis Envio 24 H Reply furosemide moa 6:45 PM on November 12, 2021 cialis y viagra Reply seensible 5:15 AM on November 12, 2021 lasix dosing Reply priligy dapoxetine review 4:57 AM on November 11, 2021 Informacion Sobre Viagra Reply myloazy 9:02 PM on November 10, 2021 Priligy Reply Haphype 6:06 PM on November 7, 2021 Stromectol Reply vivaquaxy 1:22 AM on November 7, 2021 Cialis Reply cialis pills for sale 3:11 AM on November 6, 2021 Doryx Bacterial Infections LegallNew York Herald Report on Alleged Submarine Attack
(Extract from NEW YORK HERALD of Thursday, August 2nd 1917).
TEXT of Rear Admiral’s Account of U-BOAT ATTACKS is made Public.
WASHINGTON,D.C.,Wednesday,- Details of the attacks by Prussian submarines upon the first expedition of American troops sent to France2 became known for the first time to-day when the report of Rear Admiral Gleaves, commanding the naval convoy, was made public by Josephus Daniels, Secretary of the Navy.
“I am sending you the exact text of the report of Rear Admiral Gleaves giving in detail the account of the submarine attacks for the use of the Naval Affairs Committee. I am also sending you a copy for the press exactly in the words of the official report, the only changes being that the names of the ships are


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Throughout history, Black magick, curses & hexes have also dominated the topic of Witchcraft. Today, let the truth be known about curses in Witchcraft.
Along with some of Lady of the Abyss’ own personal experiences with curses and some useful advise whether you should curse or not. What do you think she will say?
We hope you find this pod session very useful and informative.
We Had Some Technical Issues But Finally Today’s Divination Are Finally Up…..


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The Spiritual retreat or quiet time is a very calm session with the Lord Jesus away from the noise of this world and its worries. In it you listen to God as He converses with you through the Holy Bible verses and this is what Bishop Youannis had mentioned, that "Through prayer we converse with God, and through the study of the bible, He converses with us."
Do you realize my beloved that sitting under the feet of the Lord is the ultimate honor for the believer in his or her life?
O what great and blessed privilege for the believer to be in the presence of the Lord and to talk to Him. This is what led St John Chrysostom to say: "Whenever we pray, don't we speak to God?What great privilege is that?"
This is the spiritual quiet time that we are referring to, do you feel you want to enjoy and receive this privilege?


According to " The impact of face-to-face interaction at events and trade shows is unmatched and undeniable, so how can businesses leverage these opportunities to grow brand recognition and loyalty?
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Keep the conversation going: The end of the trade show is the beginning of a new or newly advanced relationship–so keep it going!
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He was taken draft. In 1988, Shaw signed a one-year contract with the Celtics. In 1989, Shaw signed a two-year contract to play with an Italian team, Il Messaggero Roma. At the end of January 1990, Shaw signed a 5-year deal with the Celtics. In June of that year, Shaw told the Celtics he planned to play for Il Messaggero during the 1989–90 seaso
Shaw joined the Los Angeles Lakers in 1999, re-uniting with former Orlando teammate Shaquille O'Neal. He served as a backup to All-Star shooting guard Kobe Bryant throughout the season and playoffs as the Lakers had the league's best record winning 67 games. Shaw played in all 22 of the Lakers' playoff games as they advanced pas fac In game 7, the Trail Blazers lead 75-60 in the fourth quarter. The Blazers shot 5 for 23 in the final quarter as the Lakers made a comeback bolstered by two clutch three-point baskets by Shaw. The Lakers won the game and made the NBA Finals to face the Indiana Pacers. Shaw started in game 3 in place of the injured Bryant, and then played critical minutes in the Lakers overtime win in game 4. T
S was later promoted to associate head coach
On June 26, 1in a car accident in Nevadar. Shaw's wife, Nikki, is a professional chef. They married in 1998 and have&oldid=1010463461"
Uses material from the Wikipedia article Brian Shaw, released under the CC BY-SA 3.0 license.


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Scientologistsfocusing on the prescription drug abuse epidemic.
Press Release - updated: Jul 6, 2017
Scientologists active with the Sacramento chapter of the Foundation for a Drug-Free World handed out copies of Truth About Drugs booklets to some 800 people attending the festival. And they reached out to children and teens, inviting them to pledge to live drug-free.
On June 26, the Church of Scientology Sacramento hosted an open house and community forum on prescription drug abuse. Attending were faith-based leaders, and Scientologists who volunteer year round to tackle this urgent issue.
Agents from spoke of how painkillers are fueling a rise in heroin use. They said the common misconception is that because they are medicine, these drugs are somehow “harmless” results in their abuse and contributes to the recent spike in overdose deaths.
Emphasizing the destructive influence of drugs on individuals and society, Scientology Founder L. Ron Hubbard wrote, “The Planet has hit a barrier that prevents any widespread social progress: drugs and other toxic substances.”
Tags: Church of Scientology Sacramento, drug abuse, drug overdose deaths, Fentanyl, Foundation for a Drug-Free World, heroin, opioid abuse, prescription drug abuse, Truth About Drugs


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ATLANTA—CoOverall beverage volume for the quarter rose 1 per cent, boosted by an increase in non-carbonated drinks. Iaw soda and non-carbonated drinks each decline by 1 per cent.
Coca-Cola Co.’s third-quarter net income fell 14 per cent.
McDonald’s gets some good news, as profit beats expectations
R12.14 billion, according to Zacks.
Coke, Pepsi, Dr. Pepper pledge to reduce calories from soft drinks


utilities industries. totality expert commercedevelopmenttotality volvmoreover r requisite architects to intentionfetchtion </s> We can still learn a lot from Washington's Farewell Address.
For most of American history, the Farewell Address was required reading in grade schools across the nation and was continually invoked in the public discourse.
The Farewell Address is mostly known for its warnings against p’s youth. Certainly, Washington made those points and offered practical advice on a wide array of other subjects. They include making permanent tle.
Wise though these recommendations may be, they underscore deeper philosophical arguments. To reduce the document to mere policy prescriptions misses the point. Besides, not all of them were meant to last forever.
If that’s the case, what can we today gain from reading his valedictory message—something that hasn’t changed since 1796: human nature.
Washington warned that America’s opponents, both foreign and domestic, would pose as its advocates.
These were the hallmarks of America’s domts.
Washington founded a nation based on humanity’s highest ideals—liberty and equality every nation which is yet a stranger to it.” It would increase liberty’s appeal to a global audience and, therefore, t


"We remain confident that with the growth in generation this will bring, alongside contributions from other technologies like solar, tidal power and hydro, the 100% remains within reach."
"If we are to meet that, it is imperative that we act now to ramp up the decarbonisation of our heat supply, which makes up more than half of Scotland's total energy use."


When do kids learn to spit — and why is it important that they do? Experts weigh in
It takes years for kids to figure out how to spit — but it's an important skill. (Photo: Getty; illustrated by Nathalie Cruz)
There will no doubt come a time when your child spits more than you'd like (especially when their target is a sibling and not, say, the bathroom sink). But parents of young children may not realize that spitting is a skill that can take years for kids to develop, and can affect everyday activities like brushing teeth and eating food.
"Spitting is a very complex action involving the muscles of the mouth, tongue, exhalation of air from the lungs and a mental awareness of why and when to spit appropriately," explains Dr. Gary Liu, a board-certified pediatric dentist. "Children develop and grow at different paces and timelines, so learning to spit is different between different children."
Liu says that most of the kids in his practice start to spit around the age of 3 or 4, though some begin as young as 2.
"At this age, they are gaining more skill in their sensory motor functions and can actually control their bodily movements more and more," he tells Yahoo Life. "They are also understanding why we need to spit and when to do it appropriately."
Regardless of the age, it's an important skill for children to develop and one that needs to be practiced.
When it comes to having kids brush their teeth, spitting is important to prevent swallowing toothpaste, especially if it contains fluoride. Bear in mind that your kiddo has probably swallowed toothpaste before (and maybe still does to some extent). Although that's generally not worrisome, it's still a behavior you'll want to curb before it becomes a habit.
"If fluoride toothpaste is swallowed in small quantities, there are no effects on the body," Liu says. "However, if a large amount is swallowed in a short period of time, one can expect symptoms [including] stomach pain, nausea, vomiting, abnormal taste, drooling, headaches, tremors, weakness or cardiac arrest in extreme cases." It would be considered a large amount if a young child swallowed an entire tube of toothpaste.
"Do it together over the bathroom sink. Even consider plopping a bit of toothpaste in the sink as a target to aim for — or you can try hitting the drain," advises pediatrician Dr. Harvey Karp, founder and chief executive officer of Happiest Baby.
You can also make it a bit more fun by doing "target practice" or having them aim for something that is father and farther away to get the idea of force, Scott suggests.
Where should my kid spit?
This depends on the situation, but common places include the bathroom sink, toilet, garbage can and so on. If it's an emergency then spitting anywhere is appropriate, but for the most part it's something that's usually done in private.
After learning how to spit, some kids take this new skill and use it outside of the appropriate context. For example, if a child gets frustrated they may begin to spit to express their anger. It's important to make it clear that spitting is not a communication device or a way to express their feelings, and should only be used when brushing their teeth or eating.


 as we misjudged some of the depths!
Look at that risky behaviour!
It's not just birds at Bolton Castle. By the car park, at the top of the hill, you can see the resident wild boar. My, these things are noisy!We made feeding time and got to listen to the ear piercing screeches of the babies fighting for snacks, not noticing the pheasant pinching their pellets from behind them!
Back in a time when it was quiet!
We then made our way back to The Board Inn for a delicious dinner cooked by Jane, and a few drinks. The best part about The Board Inn is where it got its name. Slotted behind some of the seats are board games: chess, draughts, dominoes, and probably more that we didn't dig out. As I had annihilated Dan in our last chess game, he challenged me to a rematch, and we subsequently drew the attention of half the pub, because apparently, no one ever plays the board games!Before I knew what was going on, I was playing chess against Dan and a ton of pub locals. I lost!
6 thoughts on "Yorkshire Dales Itinerary: Aysgarth"
I loved reading this!It sounds amazing!
Oh wow!That is so beautiful. I love destinations that have a lot of beautiful things to see. Especially in nature!
Love it here. So cool that you've done these Yorkshire itineraries!I live in Yorkshire and it's great to write about home sometimes!


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Yezz Chico 2C
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This device is also known as Yezz YZ202
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Why did the NEB approve the Kinder Morgan pipeline if its economic impact is negative?
Ki.


Aerosmith Going Late Night, Release Video and Talk Slash Artwork
. (hennemusic) Aerosmith has a lot of recent activities and news with the impending November 6th release of their new album including the release of a new video, news they will be playing a late night TV show and also a bit of Slash trivia related to the new album's artwork.
Aerosmith have released a video for "What Could Have Been Love," a track from the forthcoming album. You can watch the video here.
To help launch the album, Aerosmith is also set to appearNovember 1.
And finally we learn something interesting about the album artwork when Steven Tyler and Joe Perry were guests on the ITV/BBC program, The Jonathan Ross Show and they took their first look at the finished CD packaging for the project, which features inside artwork by Slash.
"" explained Tyler, "and'Can I buy that?' He wouldn't sell it…but we used it on the album." Check out the interview here.


You will believe that Sharks can fly!
African Shark Eco-Charters invites you to a place where you believe that sharks can fly!
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The thoughts and opinions of Bill Hall, Libertarian Party activist and candidate, on public issues and policy, Libertarian Party campaign strategy and his campaigns.
an.No4 PM
Thanks for all the hard work. I really mean that as I felt good voting for someone with common sense for once.It's a shame the media has such ignorance and special interest in the 2 major parties. They never give 3rd parties any direct voice to the people. Even during the governors race they didn't allow 3rd parties at the event.I think if we can work to get the Libertarian message out to more people and educate them more that we may reach a size where the media starts taking us seriously. If that were to happen, the exposure would surely allow the party to grow even more.Thank you again for standing up for freedom, principal and common sense.
Is the State Seizing Kids for Profit?
My Priorities, If Elected


Under the close eye and coaching of the legend that is Monica, beautiful young wrestler Ivy Rain is coming along just nicely.
She is developing her repertoire and skills all the time and getting stronger and wilier whenever she sets foot on the MWC mats.
But her brilliant coach isn’t satisfied and wants to see just how far she really has come…and no doubt to show her a few more tricks along the way!
Dressed in one pieces and tights, they both certainly look the part and both seem ready for battle as they square up to one another on the mats.
As we suspected though, it is clear right from the start that Ivy is in for one long tough encounter as Monica gets straight to work, taking her down and flipping her over before executing those immense skills the veteran has honed after years of brilliance in the scene.
Ivy gets a taste of Monica’s grapevine pin, body scissor and head lock before she succumbs and has to tap out for the first time.
The lesson, of course, has only just begun so Ivy gets to experience more of Monica’s lethal attacks which include figure four head locks, more body scissors, leg locks and breast smothers which bring about more submissions in the coaches favour.
That’s not to say Ivy didn’t have her moments though! Monica sure as hell felt a vicious body scissors and head scissors that her pupil locked on which earned very reluctant tap outs - we guess at least Monica has the consolation of knowing she is teaching Ivy well!
But for the most part this was very much a case of Monica schooling her pupil. Ivy has shown she is learning very quickly - a rematch further down the line will be very interesting!


Do you need a lesson plan that illustrates how you’re using differentiated instruction in your classroom? We’ve created a free lesson plan you can use with SmartMusic’s free version.
This plan, created with a young band in mind, leverages Brian Balmages’ Falcon Fanfare to work on dynamics. The lesson plan includes in-class activities and specific assignments that use differentiated instruction techniques. It also provides suggestions for creating an assessment rubric.
This Differentiated Instruction Lesson Plan Includes:
- Sequenced activities that include a warm up, pair activities, and rehearsal time to work on a section of Falcon Fanfare.
- Clearly explained differentiated instruction strategies, including scaffolding, compacting, and student choice.
One step that isn’t explicitly covered in the plan is the act of building a custom rubric to make sure you can assess your students. Here’s how to create a custom rubric in SmartMusic.
While these activities offer ways to use differentiated instruction in your classroom, SmartMusic also offers you a way to give every student practice feedback – the ultimate in differentiated instruction. The assignments detailed in this lesson plan will get your students using technology and improve their practice habits as well.
Don’t have SmartMusic yet? Try it free!


& Breakfast accommodation, is situated overlooking Courtmacsherry Bay and Harbour View Beach in West Cork Ireland. We
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Betsy Sansby, a marriage counselor with over 30 years experience has cloned herself in an iPhone app. Express Yourself Ecards help people talk about sensitive subjects from a comfortable distance without a therapist in the room.
After enough of her client couples asked “Can we take you home with us?” Sansby realized their question was serious. She


I was diagnosed with strep throat on Monday, December 12. The doctor prescribed penicillin and by Wednesday I was feeling a lot better and by Thursday the sore throat was gone. Last night before bed my throat started hurting again and this morning I woke up in terrible pain and feeling even worse than I did on Monday. I went to the clinic and they said that the swab was highly positive for strep. So now they've put me on cefprozil which they said should knock it but may not. If not I'm not sure what the next step is. Has anyone here ever had a strep infection that doesn't respond to antibiotics? I feel horribly ill and Christmas is in one week!
How long have you been taking the new antibiotic? It usually takes a couple of days to see improvement, as you found with the penicillin.
Gargling (then swallowing) soluble aspirin can help with the pain, assuming you don't have any reason not to take aspirin. And a chlorhexidine mouthwash is a good gargle if you find that you get really bad breath.
On December 12 I was prescribed a 10 day course of antibiotics (penicillin). I took the doses at the appropriate time. On December 18 I was started on cefprozil and I have now had 5 doses (2.5 days) worth of it with no improvement. Throat is still killing me, still spiking fevers, very weak and shaky. I am starting to think I should go back in because this is obviously not working.
Do you know why they stopped the penicillin early? For a resistant bout it's not unheard of to not see improvement for several days but, if you're concerned, then definitely go back to them. Do you know if they ordered sensitivities with the culture? That's really the only way to tell if you're getting the correct antibiotics if you have a strain which is resistant to the common ones.
They stopped the penicillin because I'd already been on it for 6 days with no improvement. Tuesday evening I ended up at the hospital for 8 hrs (from 4pm to 12am) because my fever spiked to almost 104 degrees. When they saw that they took me right back to treatment. They did a bunch of blood work and put me on IV with saline fluid, steroids (to decrease the swelling in my throat because I couldn't even swallow my saliva), some kind of stronger antibiotic, something for nausea and a couple different things to stop the fever. There was a bit of a scare when my temp dropped 8 degrees in an hour and a half when they gave me meds. It was down to 96 degrees. It ended up going down to 95 degrees. They said to give it a few days to go back up to a normal level. It is hovering around 96.5 now so that's not too bad. They said the infection is on its way out but for some reason I was stuck in a high fever and that the reason my throat hurts so bad is that there are open sores on my tonsils. They sent me home with a prescription throat gargle to use every 1-2 hrs and a prescription for oxycodone. The fever hasn't come back so I am happy with that but I still very, very weak. When I got home from the hospital I went to bed and was woken up at 5am with my oldest two vomitting so they've been home the last two days. I banished them to the basement recroom so we didn't expose each other to anything and they seem to be feeling a lot better. Just hoping Christmas will bring health to us all!
Glad things are slowly improving. You've had a rough time! I hope you and your kids are well enough to enjoy Christmas.


The pandemic isn’t over. We don’t know when it will end. An uncertain future means it’s time to look for lessons on how to avoid losing hope.
The UK is going back into lockdown. Sort of. It’s not the kind of lockdown which Melbourne just successfully endured, allowing them to tame a rapidly accelerating outbreak and drive the number of new cases down to zero. It’s not the kind of lockdown Adelaide went into when it appeared a dangerous outbreak was threading there.
Rather, it’s a lockdown full of exceptions, and protests, and general lack of compliance. But it’s a lockdown all the same. We’re told it’s until early December. Most people expect it will be longer. Possibly lasting the whole winter.
We got picked for a random test. The courier arrived this morning to pick up the sample. He wasn’t wearing a mask and stood under the arch of our doorway expecting me to hand the parcel to him. We need to redefine our sense of farce and irony to accommodate the idea of someone sent by the government failing to follow basic health safety in the middle of a pandemic.
All this raises the question of how to cope, how to hold onto hope, and how to carry on living well with such an uncertain future ahead of us.
When news of viable vaccines hit a few weeks ago, it was disconcerting to see how plans for summer 2021 started trending on social media. So many people seemed to expect that, come May, life would be totally back to ‘normal’, and it would be a summer full of festivals and parties.
We’re still not close to any vaccine being rolled out at scale. And the effort required to ramp up production to the number of doses needed for restrictions to go away is going to be epic.
And when the vaccine starts being rolled out – assuming you’re in a country that does this well – you (and I) won’t be the first to get it. We’ll be waiting in line behind healthcare workers and front line staff.
When the pandemic started, many expected it to be over by the summer. Then they expected it to be over when schools and universities went back, then by Christmas. If those predictions were so wrong, why expect fresh predictions like summer 2021 will be right?
Those predictions were hopeful. But they were wrong. Because that’s not the right kind of hope, the kind of hope we need right now.
Imagine you’re lost in the wilderness. Conditions are bad. You don’t know how far it will be to safety. How do you avoid losing hope? How do you keep going?
Blair Braverman’s answer is to ”act like you’re going forever.” I mentioned this in a recent post on having a good mindset, but it bears repeating. If conditions are difficult and uncertain, then the safest strategy is to assume the journey will be long.
Don’t get lured into the false hope and inevitable disappointment of expecting rescue to happen soon.
We find a similar message in Viktor Frankl’s haunting book, Man’s Search For Meaning. Writing fWW2, Frankl tries to understand what allowed some people to survive and others to give up.
At first, everyone felt lost and full of despair. But some struggled to move on. In terms of stages of grief, they were stuck in denial and negotiation. They found hope in fantasising about how circumstances would change, perhaps through imminent escape or rescue. Their spirit broke when that didn’t happen.
The people who coped better were more internally motivated. They focussed more on what life meant to them rather than what life was supposed to do for them. They were better able to find small moments of humour or joy amid the horror. Or they focused on the tasks they could do, given their situation, which added meaning to their days.
Of course our situation isn’t as brutal or stark. Lockdowns and quarantine are nothing like concentration camps. But Frankl wrote from the harshest of human experiences in order to inspire all of us when we faced suffering and uncertainty in our own lives.
The struggles didn’t end once people regained their freedom. Frankl said survivors often returned to society with complex feelings of bitterness and disillusionment. The world didn’t seem to care much, either about the suffering that they’d gone through, or human suffering in general. This made many survivors feel bitter. And freedom wasn’t as wonderful or free from suffering as they had hoped, which made them disillusioned.
Having fun wasn’t enough.
Again, the internal motivation, your personal “why,” was what mattered. Just having freedom wasn’t satisfying. A clear sense of why freedom mattered, what do with that freedom, especially in ways that helped and supported other people, gave survivors a sense of meaning that helped them enjoy their lives again.
One day this will all end. We won’t “go back to normal.” We’ll emerge in a new reality. A changed world. How do we hold onto hope now and develop a mindset for that future?
1. Believe in a better future. This will end one day. Restrictions will ease. Freedom will return. We’ll be able to move and connect again.
2. Accept that it might take longer than expected. Disasters don’t conform to our timetables and wishes. We should avoid false hope that it will end quickly or conveniently. So plan your life assuming it will last a while and set yourself up to cope with that.
This has been a year like no other. There’s been plenty to make us question human nature, but also so much innovation and inspiration as people respond to the challenges before us. There are reasons to be hopeful. But we also need to clarify what we hope for. Then make that happen as the world opens up for us again.


As the planet Bajor takes steps to join the Federation, Deep Space Nine is confronted by political turmoil and religious conflict, and Commander Elias Vaughn and the crew of the U.S.S. Defiant journey through the wormhole to explore previously unknown regions of the Gamma Quadrant.
 she orders her first officer to board the USS Defiant and defend the station.
Starfleet sent Capta, t Seventy-eight of the 1,300 aboard are abducted, including Sisko’s daughter, Rebecca.


At RMB, we believe in promoting real stories from Indigenous peoples every day of the year!
"I remember when I first started to speak publicly, I said: When you lose the language, the nation dies. People are teaching their language now. It is open in the school system. That is one of the most beautiful changes I have seen in my life, my people are teaching their language again."
"National Indigenous Peoples day is June 21, 2019. It is on this day that we take the time to celebrate the culture and contributions made by First Nations people. I am a proud Cree womanMy Cree cultures and values have guided me on my artistic and educational journeys. Today I am celebrating my Grandmother Rose Auger, who was a residential school survivor. Her stories and traditional teachings are what will carry me and my daughter throughout this life."
"I am inspired by the resilience, humour and non-critical nature of the Indigenous people. They have been displaced by the settler society and were subjected to the genocidal policies of the Canadian state, and yet I never detect any animosity in discussing their difficulties. They just express a need to be understood and to improve their present circumstances. They don't want revenge. They just want what is fair. This to me is the essence of restorative justice, and it motivates me to work towards replacing punitive measures with restorative ones."
"I read the stories of First Nations like I read the instructions on a fire extinguisher: critical instructions on how to get ourselves out of a climate and nature emergency when the planet is burning."


Kelso Cottages
Any rugby fans? The Kelso Rugby Club boasts one of Scotland's finest grounds, so if your Kelso cottage holiday falls when there's a match on, do consider going. The sport is so popular here and the atmosphere at a match is simply amazing.
In a nutshell, something for everyone!


Download a sample from Peter d'Plesse's new book!
Peter d'Plesse's Fire Eye is a compelling Australian outback adventure story about a driven and complex young woman who engages a part-time adventurer to help her find her grandfather's lost World War II aircraft in northern Australia.
Both of my novels share two main characters in the form of Alexander Dulaine and Jed Mitchell. They each have baggage and qualities...


Chief secretary Ashok Nath even had a review meeting on Monday after first youngster was fined Rs 1000 on 14 February, the Valentines Day, for smoking at the Panaji bus stand. Since then, the drive has been intensified.
Within a fortnight, the police penalised four smokers and 24 shopkeepers, collecting Rs 30,000. "We will intensify it further, by initially concentrating in cities", says D C Srivastav, the SP (CID).
Nath, the chief secretary, also admits the fact stating that the enforcement would be difficult in view of the typical geographical location of Goan markets. He has thus instructed the authorities to carry out a systematic campaign with no intention of harassment but to build consciousness..


More than 1,800 New Yorkers are currently enrolled in a court-ordered outpatient treatment program through Kendra's Law. According to Brthe Mailman School, director of the Center for Youth Violence Prevention, and lead investigator of the study, there are clear benefits to such involuntary care. "Our study has found that."


Month wise coverage of Summits & Meetings Current Affairs helps you improve your general knowledge and prepare for all competitive exams like IBPS, Bank PO, SBI PO, RRB, RBI, LIC, Specialist Officer, Clerk, SSC, UPSC, Railway etc. This section is updated daily with the most important events.
Preparing Summits & Meetings Current Affairs January, 2016
▼ India France Business Summit held at Chandigarh   [01-25-16]
PM Narendra Modi has addressed the India France Business Summit in Chandigarh appreciating the manner in which the CoP 21 negotiations have been coordinated. PM Modi also recalled a terror attack in Paris just a few days before CoP-21 meeting and how France has shown the way to combat terror without deviating from core principles. Linking security to the defence sector, Indian talent and French manufacturing capability can ensure that the world becomes a secure place. Around 16 agreements and MoUs were exchanged at the summit.
▼ Russia signs new anti-terror law   [01-4-16]
Vladmir Putin has signed a fresh anti-terror law permitting members of the security forces to open fire on suspected women, children and disabled terrorists. Amendment to the rules governing the use of force by Federal Security Service has been carried out. Intelligence agents will now take fingerprints on state borders and conduct searchers of any property in the event of suspected terror activity.


I would like to thank you and the team for your great communication and for sorting us out with a great system with no fuss and without any problemks to all of you for your prompt service, we're very impressed.to find at the home show someone who was prepared to give information without the need to have a consultation in one's home.
I spoke with Kev who gave all the information I need without being in the least 'pushy' or the need to make one feel like an idiot. He was knowledgeable about your products and sold your products by their merit.
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We stayed here because we had an international flight out. Everyone was great. The rooms are very basic but the water pressure was the best! I wish there were closer dog potty areas but we made do with it.
We haven‘t received any photos of Miami International Airporami International.


A spokesman for the mayor said: "No one is allowed to throw their rubbish in the street and Porsche should not be allowed to impose gas-guzzling polluting cars on Londoners who do not want them."


The lights in the city went red green red in the puddles of oil glistening in the cooling Autumn sun, Los Angeles, walking along the suppertime sidewalk, Hunter prowled head down, needing air, strangers, the ever busy and indifferent outside world, the simple flowing motion forward of stepping after struggling for hours alone on his computer in his clean, organized, solitary apartment. The basic problems of language tonight could not be resolved. There was no expressing what he needed most directly to say. There were side avenues, right angles to that direction, but it was like poking a needle at a vein in the dark. Added to the basic fact that he wasn’t even sure what he wanted to say exactly, just knowing that he needed to. And then the heavy stillness of his loneliness pressing in around every spark, making it difficult to catch even the draft of one opening sentence, nothing insubstantial tindered–all thoughts were vital, boundless, and opaque to immediacy. He stopped and fingered out a Kamel Red Light and lit it and blew out smoke steadily, standing before a pink staccato hanging plant infested apartment complex lined with projecting rectangular balconies from which smells of various take-out and stove-cooked foods emanated. He watched a pretty woman across the street talking on her cellphone and looking up and down the street, waiting to be taken somewhere. He breathed in smoke and held it deep in his lungs and blew it out at the sky. He wasn’t a nicotine addict, but there were times in the streets that he needed the cigarette excuse to stand and meditate in the midst of so much apparent purpose. The many cars sleeping along the curb were glistening with lights in the descending dusk. Smells of foreign worlds, flowers mingling with the dinner street Fall smells.
Hunter continued down the blocks, listening to the fragments of peoples lives spilling into an atonal polyrhythmic flow of city life. Always everywhere something there to let you know that you are a piece of something less and something greater. There is you and there is me and the in-between is but a matter of beginnings and endings which have no distinction. Here is the rich and here is the poor and here is the hunger and here is the denial and here is the ever looming threat of the crowd boxed in, separated and policed mainly by the mind–the danger is felt when the eye is opened and the reality stirred. The blinders of everyday indifference are the city’s lifeblood, it’s basis of existence. Alien human beings are traffic, they are passerbys, they are herds and individuals, they are box office ticket buyers and supermarket cart wheeling hobos, jazz club afficianados Hollywood industry junkies. They are a force contained and exploding in windows all across the night
Well, it made him stronger, Hunter felt. It destroyed him as he loved it. It recontructed him as he hated it. And even when the voice within him couldn’t find its way into this overlying structure, simply walking through the solitary streets and breathing the electric air soothed him to an unrequited silence. Where the inner ground of integrity was known, with no verification, with no credits and no communication.


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Navy Skinny Fit JackChoosyConsumer from Great suit Great quality and washable. My teenage son loved the cut - but it was very dark in colour. Less navy, more a blue-black. Arrived very promptly and well packed.


- NJIT will be hosting a symposium & workshop by AIA Regional Recovery Working Group entitled “Post Sandy: the Effect on the URBAN” on July 9, 2013. More.
- The 5th annual AIA-NJ Fall Symposium, “Distributed Intelligence”, will be on Wednesday, November 14, 2012 from 1:30 – 5:30 PM. More.
- Three third-year Interior Design students from the School of Art + Design were selected as one of two winners of the 2012 “Through the Decades” Chair Design Competition sponsored by Kimball Office Furniture. More.
- CoAD recently hosted the jury of the international student design competition called “Integrated Communities: A Society for All Ages”other partners. More.
- Zeynep Celik, distinguished professor at the NJIT College of Architecture and Design, published a new book that was co-edited with Zainab Bahrani and Edhem Eldem,SALT in Istanbul:”. More.
- “HD’s the Urban Design Merit Award in AIA New York's Design Awards. More.
- Zeynep Celik, PhD, distinguished professowon theher project “Empires and Antiquities: Appropriating the Past.” More.
- Glenn Goldman, founding director of NJIT's School of Art + Design, has been appointed Education Liaison to ACM/SIGGRAPH 2013 to be held in Los Angeles. November 15, 2011 More.
- . August 31, 2011 More.


Detroit's next big name in burgers is almost there, and on Saturday, actor Mark Wahlberg stopped in to the currently under construction Wahlburgers location in Greektown.
Wahlberg stopped in on Saturday with cameras to be featured on the hit show by the same name on A&E network. The actor tells us the food choices will be delicious when the location opens around July 20.
When asked by he picked the Motor City as the newest Wahlburgers location, Wahlberg said, "It's just good hard working people, and it's like Boston and it's a hockey town like Boston. Not a lot of them left in America."
He is also in town filming scenes for the upcoming Transformers movie. Wahlberg also said that people should come out and hangout with him and his crew, and they will be down there every night hanging out.


Home / News / Top 10 Fastest Luxury Sports Cars in the World!
cars › cool › exotic › fast › new › rare › sleek › sportscar › Share: Recent Articles

8) Pagani Huayra ThZe 6) McLaren F1
This extremely rare car is a little older than many of the worlds current fastest cars having first been manufactured sever decades ago, however, it still holds its place for one of the most high-speed cars on earth at 243 miles per hour!
5) Koenigsegg CCX
Bugattis are world renown for manufacturing and designing some of the fastest and most luxurious modern sports cars. This high class Vitesse can go up to 254 miles per hour and glides through those curves like butter!
2) 9ff GT9-R Th! 1) Bugatti Veyron Super Sportr! !


8 thoughts on "Environmental Terrorism"
Oh yes!You are asking the toughies!Excellent…Yet, no comments?Hopefully, silence is golden because you are stirring thought!
I am an eternal optimist – naive maybe – but deep inside each person has to be a spark of the divine – just needs to be ignited – then their choice whether to act or not – whether to hear conscience – so, hopefully, provoking and prodding in uncomfortable areas shifts the veils, blows the cobwebs and gives opportunity!
Maybe, but the way I prefer while I have the option – and I am grateful to have the option!Especially living here in South Africa!
I respect that fully!
Interesting!I also grew up trusting and believing in people and had a huge shock when I realised my perspective was not what the reality seems to be!I have since come to accept, for myself, that we choose our perspectives and to a large extent, our realities. Each of us see the world our own way and, as you say, I respect that fully, even if it's not the way I see it. Each to our own – and what one person may see as 'good' is not necessarily the same as the next person. Same for everything (love, hate, religion, God, source, energy, life, etc.), and that's okay not so?I can only really be concerned with my own thoughts and actions – therein my responsibility!Just how I'm seeing things now – which can change too!Isn't life great?


, we're going to see_ _how media played a role in setting the stage for American involvement in international conflicts."_
Oneducational theory
was. Before the advent of cognitive studies, the prevailing learning theory was behaviorism, which
concentrated on the role of outside stimulus as a mechanism for learning. The publication of _A Study of Thinking_ (Bruner, Goodnow, & Austin, 1956) led the way for exploration of what happens inside the minds of learners and how they organize and use information. Over the course of the next 50 years scientists, **19**
psychologists, and educators have examined memory, emotion, schema, and
experience as essential components of learning. In fact, the influence of cognitive science is so profound that it now may be difficult to conceptualize how the process of learning was perceived in the first half of the century. This book, for instance, is replete with learning approaches that reflect our profession's roots in cognitive science—scaffolding, metacognition, accessing background
knowledge, and transferring of learning—to name a few.
Types of Anticipatory Activities
One aspect of learning theory that has received a great deal of attention is (please par-don us now) "attention." Anyone who has ever faced the task of teaching a group of people can appreciate the importance of attention as a factor in learning. After all, if students aren't paying attention, how can they process new information?
When we speak of attention we are not referring to behavior management, but
rather to practices that el of newly learned information. In addition, attention also means activating students' background knowledge about the topic. This is really the very beginning of the learning process, although it is not bound in time to the beginning of a course, class, or lesson. Therefore, anticipatory activities should be tied to the introduction of new concepts, and not simply to the first 5 minutes of a class period. Good and Brophy (2002) remind us that effective teachers create memorable events throughout their lessons to capture student attention, not unlike the teacher in the opening vignette for this chapter. However, it is essential to note that gaining attention through anticipatory activities is not intended to provide entertainment for students, but to scaffold learning so that the cognitive A primary goal of classroom instruction is to moveg. Anticipatory activities can ground new learning in meaning-based inquiry because the student's attention has been gained through an event connected to the purpose for studying the topic.
These memorable events may also
use drama, humor, movement, or emo-
**HAVE RICH BACKGROUND EXPERIENCES**
tion to make an impression on learning.
Eggen and Kauchak (2001) suggest
As Broaddus and Ivey (2002) noted, knowing students as readers,
four instructional routines for gaining
maintaining a wide range of reading material on topics under in-
student attention:
vestigation, and allotting time for reading in every class can support
readers regardless of motivation, interest, or ability. An important
1. demonstrations,
way of knowing students and connecting them with reading material
2. discrepant events,
is to activate and build background knowledge. Quick writes, for ex-
3. visual displays, and
ample, allow the teacher insight into students' thinking. Classroom
4. thought-provoking questions
discussions using K-W-L or other language charts provide information
about students' background and prior knowledge such that the
teacher can find reading material that students can and want to read.
We will discuss each of these in
Visual displays also help struggling readers develop their under-
detail and then take a look inside class-
standing of the content as they discuss this type of information with
rooms to see how teachers across the
their teacher and with one another.
content areas are using these anticipa-
tory activities to stimulate curiosity,
build background knowledge, and promote learning. But first, let's consider the **BACKGROUND**
use of anticipatory activities for English language learners.
Classroom demonstrations are typically performed to display a theory, concept, or phenomenon. A demonstration of gravity is likely to involve dropping objects
from a height; a demonstration of fractions and decimals might include several apples sliced into equal parts. The use of demonstrations is critical in the field of mathematics (Lee, 2000) and is associated with higher levels of learning in science (Beasley, 1982). Don't overlook the availability of technology to enhance demonstrations of complex phenomena (Brooks & Brooks, 1996). We particularly like Web sites that portray scientific concepts. For instance, students can watch how an earthquake occurs, see the phases of the moon change, or dissect a virtual frog. One of our favorites is VisualThesaurus.com, which displays a semantic web of related terms organized by meaning and usage. The use of demonstrations to illustrate and augment lecture and readings is particularly effective for students with disabilities (Janney & Snell, 2000) and English language learners because it is enhanced by physical and kinesthetic involvement.
Demonstrations should be used judiciously in order to prevent confusion. In
particular, a demonstration is likely to fail if it is not grounded in the theoretical framework. In other words, an interesting demonstration does not replace the need for deep exploration of concepts. Also, don't overlook the importance of telling students that the demonstration is important to remember, and why. These simple statements of emphasis have been shown to be effective when coupled with
demonstrations (Eggen & Kauchak, 2001; Larsen, 1991).
**Discrepant Events**
Discrepant events are those demonstrations that involvecommand the students' attention. A performance may be
staged—for instance, another teacher may be recruited to rush into the classroom to hand the social studies teacher a copy of a newspaper dated December 7, 1941. Hurst (2001) suggests that attention-grabbing events are a key element to content area lesson planning, along with mini-lessons and comprehension instruction. She and others (e.g., Anderson & Pearson, 1984; Smith, 1998) remind us that attention is directly related to schema, the knowledge structure used to comprehend. Events such as these can assist students in organizing new information, integrating it with prior knowledge, and increasing their ability to retrieve it later (Landauer, 1975).
The use of anticipatory activitiesas they activate background knowledge. Background knowledge is related to the unique experiences that each student has, such as living in places where it snows, the look of a wheat field, or what it feels like to surf. It is also the formal learning that students are expected to have. Anticipatory activities help activate this knowledge for students by providing them ways to connect their experience and new information. As Rothenberg and Fisher (2007) note, building background knowledge is critical if English language learners are to be successful in academic classes.
Discrepant events also access a powerful aid to memory—emotional connec-
tion. As humans, we have a tendency to remember episodes connected to our emotional memories, such as a favorite birthday party or a first kiss. The associations may be negative as well—mk on America in 2001. Whereas discrepant events in the classroom are unlikely to be connected to such intense emotions as these, it is important to recognize that they tap into the same neural pathways (Metzloff, Kuhl, Movellan, & Sejnowski, 2009). Integrating music, art, and dramatic play can provide a means for **BACKGROUND**
accessing students' emot


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MIRON: When you drive it totally .
ROSALSKY: Christina learned that these swole (ph), maskless bros were refugees from big chain gyms, which had followed state orders and closed.
CHRISTINA: So I don't know how they heard about our gym, but word spread like wildfire.
MIRON: People figure out new, clever ways to get around prohibition laws.
ROSALSKY: ...Like making moonshine in your bathtub or creating a secretive workout facility in a strip mall. The longer the prohibition goes on, the more likely people will ignore it. And as the shutdowns wear on, that could mean more speakeasy gyms.
Greg Rosalskformed house/techno duo Azimute pop their musical cherry in a big way with “Control” for Crosstown Rebels, and we’re pleased to premiere their first offering to the world.
With its booming, hypnotic bass, tight percussion and robotic vocals, “Control” is simply aching to be heard on a big sound system.
Crosstown Rebels will release Azimute’s Control EP on vinyl on October 20, digitally on November 3. The pair will issue an EP shortly on Derrick May’s Transmat Records. </s>  men were gone before Harris saw the receipt. She saw the words before she saw the tip, and the words alone were enough to overwhelm her. said, “b’ </s> tion due to ‘systemic racism’, report claimsJuly 14, 2021
According to research by the Describing the recent Sewell report on racism in Britain as “divisive and dishonest”, it also claims the government’s new approach to equality “may in fact worsen” outcomes for minority communities.
It comes afterrince William were forced to condemn racist abuse of
But fellow player Tyrone Mings responded by accusing the pair of hypocrisy in light of their refusal to condemn fans booing the team for “taking the knee” against racism before the Euroshe wrote on Twitter on Monday.
The report, which used evidence from more than 100 civil society groups, found Ms Patel’s Police Crime and Sentencing Bill “particularly alarming” in terms of immigration.
These are accompanied by shadow reports from organisations such as the Runnymede Trust to help the UN with its findings.
The Runnymede report cited a rise in hate crime andcommunities as examples of government failings on race.
It claimed inequalities are worse now than they were when the previous shadow report was submitted in 2016.
Researchers also rubbished the findings of the Sewell report, which claimed there is no institutional racism in Britain and that the “
But she said: “h, ”
Source: Read Full Article </s> Pre Waters.
Waters, who has an ongoing feud with the President, made the remarks on Sunday afternoon while being interviewed by CNN. She was responding to Trump’s tweet that suggested “progressive” members of Congres Waters said the tweet should not come as a shock to anyone given he is an “illegitimate racist.”
“But don’5 the death penalty,” she continued.
“Hat


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We focus on the Alpha and Price Momentum factors in the US, Europe and Japan. Alpha is defined as the residual between the stock return and the sum of all factor contributions to the stock returns. The factors used to explain stock returns are the market, d. The factor contributions are derived via a regression analysis with a two-year lookback and monthly factor data. Price Momentum is based on the absolute stockAlpha and Price Momentum factors are created via a.
ALPHA MOMENTUM VERSUS PRICE MOMENTUM: US
The performance of Alpha and Price Momentum from 2002 has been much more attractive in Europe than the US. The chart below highlights that Alpha Momentum has generated a more consistent and less volatile performance than Price Momentum in Europe. It is worth highlighting that Alpha Momentum does not exhibit a momentum crash in 2


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Clos de la Vila House by Ramón Esteve
AASA 7 December 2021 5 December 2021 House, News, Ramón Esteve, Spain
Located on a hill overlooking a rural town in Valencia, the Clos de la Vila House is based on a reinterpretation of the local traditional gable-roof house. In order to show a contemporary look, each of the different adjoining volumes of the house have single-sloping roof facing the opposite direction to the next.
The layout of the house comes from breaking the building into different pieces that set back and create gaps at the intersections, which define exterior spaces such as entrances, terraces and porches, that in turn are covered by the extension of the roof at certain points. By extending some blocks, we create a U-shaped building with a central patio that aims to limit the space and better meet the needs of the program.
One of the main characteristics of the Clos de la Vila House is the use of two differentiated materials, both on the façade and in the interior spaces. A stucco plinth, coloured in the same tone as the local soil, rises from the ground up to eight feet in height, thus framing the openings that contain windows and doors. For the rest, we use a rough stucco in a lighter tone, with tiles in the same colour cladding the roof.
We use the same pavement throughout the house, so that the interior spaces continue to the exterior. This same material is used in the pool, preceded by wooden platforms that replicate the shape of the pool to delimit the area and make it warmer. The program is distributed on a single floor that the central access divides into two parts. The day area is located on the right, a fluid andoom, kitchen and the outdoor barbecue.
The night area, more compartmentalized and private, is located on the left and and dressing room, a master suite and a laundry room. Wood predominates in the choice of materials. It is used for both the exterior doors and windows and in a large part of the furniture. This choice seeks to bring warmth to the interior while showing a rustic but contemporary look.
The house integrates into the typical local landscape, as a Valencian garden connected to the house blends into the landscape. This is an open garden that embraces and frames the views over the town where the house is located. The access patio that welcomes the visitor is designed with a wide collection of citrus trees, while the rest of the house is surrounded by carob, cypress and hackberry trees. Source by Ramón Esteve.
Building Engineer: Emilio Pérez, Carolina TarazonaLandscaping GM Paisajistas
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Sóller is "the place" to start your hiking tours on Mallorca. The Tramuntana Mountains attract thousands of hikers every year. From short walks through orange and olive groves to propper several day hikes with layovers in mountain shelters (Refugis), everything is possible. From the romance loving hiker to the adventurous climber, everybody finds their preference.


Who is more evil—the maniacal Saudi crown prince responsible for Khashoggi's murder and the murder of tens of thousands of Yemenis, or the mendacious world leaders and businesspeople who continue to embrace what should be a pariah state?
"If Bin Salman went before a jury, he would be convicted in 30 minutes."


Abstract. Among the most expressive knowledge representation formalisms are the description logics of the Z family. For well-behaved fragments of ZOIQ, entailment of positive two-way regular path queries is well known to be 2EXPTIMEcomplete under the proviso of unary encoding of numbers in cardinality constraints. We show that this assumption can be dropped without an increase in complexity and EXPTIME-completeness can be achieved when bounding the number of query atoms, using a novel reduction from query entailment to knowledge base satisfiability. These findings allow to strengthen other results regarding query entailment and query containment problems in very expressive description logics. Our results also carry over to GC2, the two-variable guarded fragment of first order logic with counting quantifiers, for which hitherto only conjunctive query entailment has been investigated.


Let me pay tribute to Tuesday Morning Quarterback. Many of my theories regarding football are formed as I learn from the pied piper of actually thinking about what is happening, Gregg Easterbrook. Best football weekly update you will read.
 The guy that hires him as an offensive coordinator will do well. Prior to being head coach for the Bronco’s, he was the Offensive Coordinator for the Patriots during their 16-0 regular season and I loved his play-calling and schemes. He will bring success to a lucky team that snags him quickly.
More hurry up football. Defenses hate this. They love rotating people. Spread the field and snap the ball quickly.
You need to run two trick plays per game. Ken Whisenhunt was great at this when he coached the Steelers. You need to try two trick plays every game. Even if the other team knows you are going to run two trick plays in the game, it is incredibly mentally taxing on the defense when you do it. Flea flickers, reverses, reverse passes, fake field goals, designed roll-outs and bootlegs, option plays, weird direct snaps, all that stuff. I like reverse passes a lot, because I think if you are going to run a trick play, it has to be a shot. Flea flickers rarely seem to work, but the reverse pass seems to be consistently effective – I think that is because the defense on that side feels the need to come up to stop the run, allowing people to get behind them. Flea flickers pull up the safety, but cornerbacks on the edge of the play will typically simply stay with the receivers, making it a hard play to work:pread the field and snap the ball quickly.
 Pick a day man!


A Mother Box is an other-worldly, cube-shaped piece of technology.[1] At least three Mother Boxes are known to exist, with them originally being owned by Steppenwolf, but which were subsequently left in the hands of the Atlanteans, Amazons and humans.[2]
Roughly 30 millennia before the 2013 Black Zero Event, the malevolent Steppenwolf and his massive Parademon army would invade Earth, but they were successfully fought off by the combined efforts of the Amazons, Atlanteans, and humans. Before being forced to depart, Steppenwolf would leave behind three Mother Boxes, and each of the three factions of the army that helped save the Earth would be given one of them.
In 1982, S.T.A.R. Labs found one of the three Mother Boxes (presumably the one that had been given to the humans several millennia ago). 33 years later, in 2015, Silas Stone attempted to perform experiments on the Mother Box in order to help his severely injured son, Victor. Though nothing seemed to work, it eventually began pulsating, and he gave it to Victor, causing it to transform and began cybernetically repairing his son's badly damaged body.[3]
In a deleted scene called "Communion", the being standing before Lex as he is about to be arrested is holding two box-like objects in each of its hands before vanishing, suggesting that they are Mother Boxes and Lex had encountered Steppenwolf.
The Mother Box's code name is "US GOV object 6-19-82". The numbers can be interpreted as "June 1982", the month of publication of Cyborg's origin story in Tales of the New Teen Titans #1.
↑ Batman v Superman's Cyborg scene explained - Entertainment Weekly
↑ ‘Justice League': Willem Dafoe Plays a Major ‘Aquaman’ Hero - Collider


There are times when you need to format a hard drive or SSD on your Windows 11 PC. Be it for giving away the storage device to someone else or erasing all the data to start from scratch. Formatting a storage disk reduces the chances of faulty disk sectors, common disk errors, and defragments the disk. So to learn how to format a hard drive or SSD in Windows 11, we have come up with this guide with four simple methods. You can perform a quick format, erase data from all sectors, create primary partitions, and a lot more. So format HDD or SSD in Windows 11.
2. Next, in the pop-up window that opens up, make sure “File system” is selected as “NTFS“, which is a Windows file system. If you want the hard drive to be compatible with macOS as well, you can choose “FAT32” or “exFAT” file systems.
1. Simply press “Windows + I” to open the Settings app in Windows 11. Here, navigate to System -> Storage.
2. Next, expand the “Advanced storage settings” option and select “Disks & volumes“.
3. Here, click on the primary partition under the HDD or SSD you want to format. Then, select the “Properties” option.
4. Next, click on “Format“.
While Disk Management may look a bit daunting to many, it’s actually the best way to format a hard drive or SSD in Windows 11. It’s my favorite method to format hard drives, SSDs, SD cards, thumb drives, and more. With that said, let’s begin.
1. Press “Windows + X” or right-click on the Start menu to open the Quick Links menu. Now, click on “Disk Management“.
2. In the Disk Management window, you will find the connected hard drive or SSD storage, generally marked as “Disk 1” or above, at the bottom. On the right side, it will show the primary partition. Right-click on this and choose “Format“.
3. Next, give a name to the HDD or SSD under the “Volume label” field and click on “OK“. You can uncheck “Perform a quick format” if you want to actually erase all the data instead of memory references.
4. And that’s how you can format a hard drive or SSD in Windows 11 with Disk Management.
6. Now, you need to initialize the disk in order to use it. For that, run the below commands one by one. In the fifth command, where you assign the drive letter, replace X with your preferred letter. When you’re done, you can use the formatted hard disk or SSD through File Explorer.
So this is how you can erase, format, create a partition, and initialize the disk on Windows 11. I love the fact that Windows 11 has multiple built-in tools to format a hard drive or SSD storage disk. You can perform a quick format or uncheck it and erase the whole disk sector-by-sector for complete peace of mind. Anyway, that’s all for this guide. In case you’re looking for a way to uninstall apps in Windows 11 from system programs to hidden apps, you can follow our article. And for those looking to convert the disk from MBR to GPT without any data loss in Windows 11/10, head to our detailed tutorial to check out.


FKeep to yourself, keep to yourself. For some reason, this band is somewhat popular among English speakers maybe it has something to do with the fact that. 19 Jan Stream Loser by Plastiscines from desktop or your mobile device. Plastiscines | Length: Composer: Katty Besnard. This track is on the 3 following albums: Loser · Plastiscines · Lp1 · Plastiscines · Lp1 · Plastiscin.