Datasets:

ClarusC64
/

clinical-interventional-ripple-primary-perturbation-encoding-v0.1

id stringclasses 10 values	intervention_name stringclasses 10 values	modality_class stringclasses 8 values	protocol_summary stringclasses 10 values	dose_or_stimulus stringclasses 10 values	intensity_0_100 int64 35 85	duration_hours float64 0.05 1.01k	frequency_pattern stringclasses 9 values	setting_context stringclasses 6 values	expectation_context stringclasses 5 values	contraindication_flags stringclasses 10 values	perturbation_profile stringclasses 10 values	primary_system_engaged stringclasses 7 values	perturbation_axes_top5 stringclasses 10 values	encoding_evidence stringclasses 10 values	constraints stringclasses 1 value	gold_checklist stringclasses 1 value
IRPE-001	Vagus nerve stimulation	neuromodulation	tVNS ear clip 25 Hz	0.8 mA	45	0.5	daily x 14	clinic supervised first session then home	neutral framing	arrhythmia_risk=no	target=parasympathetic; lever=afferent vagal input; onset=minutes; pattern=repeated pulses	autonomic_vagal	intensity_0_100; onset_speed; exposure_pattern; coupling_breadth; monitoring_density	Direct vagal lever with fast onset and repeated dosing	Under 190 words.	1 profile
IRPE-002	Psilocybin assisted therapy	psychedelic	25 mg session with prep and integration	25 mg	85	6	single session	therapist guided room	high expectancy	psychosis_risk=screen	target=brain network reconfiguration; lever=5HT2A agonism + context; onset=30-60min; pattern=single high dose	neuroplasticity_network	intensity_0_100; duration_hours; context_safety; expectation_load; coupling_breadth	High intensity with strong context load and broad coupling	Under 190 words.	1 profile
IRPE-003	Prolonged fasting	metabolic	72h water fast with electrolytes	72h	70	72	single block	home with monitoring	mixed expectancy	diabetes_risk=monitor	target=metabolic switch; lever=glycogen depletion; onset=hours; pattern=continuous deprivation	metabolic_energy	duration_hours; onset_speed; adherence_friction; reversibility; coupling_breadth	Long duration with rising adherence friction and broad systemic coupling	Under 190 words.	1 profile
IRPE-004	Ketogenic diet start	metabolic	strict keto 20g carbs for 4 weeks	20g carbs	55	672	daily continuous	home	neutral	eating_disorder_risk=screen	target=metabolic fuel shift; lever=carb restriction; onset=days; pattern=continuous dietary constraint	metabolic_energy	duration_hours; exposure_pattern; adherence_friction; reversibility; coupling_breadth	Diet constraint with slow onset and moderate intensity	Under 190 words.	1 profile
IRPE-005	Cold exposure protocol	hormetic	3 min cold shower x 10 days	3 min	60	0.05	daily x 10	home	high expectancy	cardiac_risk=screen	target=autonomic and endocrine surge; lever=cold shock; onset=seconds; pattern=brief repeated pulses	endocrine_stress	onset_speed; exposure_pattern; intensity_0_100; reversibility; expectation_load	Fast onset pulses with high reversibility	Under 190 words.	1 profile
IRPE-006	Anti inflammatory steroid burst	immune	prednisone 40mg x 5 days	40 mg	65	120	daily x 5	home	neutral	infection_risk=watch	target=immune suppression; lever=glucocorticoid; onset=hours; pattern=short course taperless	immune_inflammatory	intensity_0_100; duration_hours; reversibility; monitoring_density; coupling_breadth	Direct immune lever with medium onset and broad coupling	Under 190 words.	1 profile
IRPE-007	FMT capsule course	microbiome	capsules x 3 days	30 caps	50	72	daily x 3	clinic prescribed home use	neutral	immunocompromised=no	target=gut ecosystem reseed; lever=donor microbial transfer; onset=days; pattern=short burst then settle	gut_microbiome	duration_hours; onset_speed; reversibility; coupling_breadth; monitoring_density	Short burst with slow settling and medium reversibility	Under 190 words.	1 profile
IRPE-008	CBT insomnia protocol	behavioral	6 sessions weekly plus homework	6 sessions	35	1,008	weekly x 6	telehealth	moderate expectancy	none	target=sleep regulation; lever=behavioral schedule; onset=weeks; pattern=repeated coaching loops	sleep_circadian	duration_hours; context_safety; adherence_friction; exposure_pattern; expectation_load	Slow onset with adherence friction and high context safety	Under 190 words.	1 profile
IRPE-009	Breathwork CO2 tolerance	behavioral	20 min daily paced breathing x 21 days	20 min	40	7	daily x 21	home	high expectancy	panic_risk=monitor	target=autonomic tone; lever=CO2 setpoint training; onset=minutes; pattern=repeated practice	autonomic_vagal	exposure_pattern; onset_speed; adherence_friction; intensity_0_100; expectation_load	Repeated practice with fast onset but skill dependent	Under 190 words.	1 profile
IRPE-010	SSRI initiation	pharmacologic	sertraline start 50mg daily	50 mg	45	672	daily continuous	home	mixed expectancy	mania_risk=screen	target=serotonin tone; lever=reuptake inhibition; onset=weeks; pattern=continuous dosing	neuroplasticity_network	duration_hours; onset_speed; reversibility; monitoring_density; expectation_load	Slow onset with moderate monitoring needs	Under 190 words.	1 profile