source_paper string | source_section string | premise string | target_doi string | target_paper string |
|---|---|---|---|---|
PMC9728410 | Current Status of COVID-19 Vaccine Development | DNA vaccine candidates targeting SARS-CoV N protein as an immunogen can generate N-specific humoral and cellular immune response [93]. | 10.1128/JVI.78.9.4638-4645.2004 | PMC387705 |
PMC9728410 | Current Status of COVID-19 Vaccine Development | Another major hurdle for vaccine development is higher mutation rates of RNA viruses compared to DNA viruses, resulting in higher genetic diversity [94]. | 10.1371/journal.pbio.3000003 | PMC6107253 |
PMC9728410 | Current Status of COVID-19 Vaccine Development | Moreover, the RBD of the S protein is the most variable region in the coronavirus genome [95]. | 10.1038/s41586-020-2012-7 | PMC7095418 |
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